Stereotactic Body Radiation Therapy (SBRT)-advancing precision in cancer treatment

Verified by Dr. Sandeep De, Consultant Radiation Oncology, at the best cancer hospital in Mumbai-Apollo Cancer Centres, Navi Mumbai.

Stereotactic Body Radiation Therapy (SBRT), also known as Stereotactic Ablative Radiotherapy (SABR), is an innovative and highly precise radiation treatment approach that delivers high doses of radiation to tumors in a few, well-targeted sessions. This cutting-edge technique has transformed the landscape of radiation therapy, offering exceptional tumor control with reduced treatment time and minimized impact on surrounding healthy tissues.

Understanding SBRT/SABR

SBRT/SABR is designed to deliver a concentrated and accurate dose of radiation to tumors, while sparing nearby healthy tissue. The term “stereotactic” (Stereotaxy – combination of ‘Stereon’ meaning 3 – dimensional/ Spatial & ‘Taxis’ meaning placing/ positioning) refers to the precise targeting of a specific three-dimensional coordinate within the body, ensuring that the radiation beams converge at the tumor site with remarkable accuracy. This level of precision is achieved through advanced imaging techniques and state-of-the-art treatment planning systems. This is implemented with a robust Motion Management System.

Which conditions require SBRT?

SBRT/SABR is used to treat a range of both primary and metastatic tumors in various parts of the body. Some common clinical indications include:

• Lung Cancer: SBRT/SABR has revolutionized the treatment of early-stage lung cancer, especially for patients who are not surgical candidates or prefer a non-surgical approach. It delivers highly focused radiation to the tumor, resulting in excellent tumor control rates. Also, metastatic lesions (primary tumor from any other organ of the body spreading to the lungs) can be treated with SBRT.
• Liver Tumors: SBRT/SABR can effectively target liver tumors, offering a non-invasive treatment option for patients who may not be suitable candidates for surgery. Metastatic lesions of the liver can also be treated with SBRT with the same precision as surgery.
• Spine and Bone Metastases: SBRT/SABR is used to treat localized tumors in the spine and bones, providing pain relief and stabilizing the affected areas.
• Prostate Cancer: In select cases of localized prostate cancer, SBRT/SABR can deliver a higher radiation dose to the tumor while reducing exposure to nearby critical structures.
•  Pancreatic Cancer: For locally advanced pancreatic cancer, SBRT/SABR may be employed to improve local tumor control and potentially increase the effectiveness of other treatments.
• Renal Cell Carcinoma: SBRT/SABR is utilized to treat kidney tumors, preserving kidney function while targeting cancerous cells.
• Head and Neck Tumors: SBRT/SABR can be considered for certain head and neck tumors, providing a focused and efficient treatment option & also in the setting of re- irradiation.

Advantages of SBRT/SABR

• High Precision: SBRT/SABR’s exceptional targeting accuracy minimizes damage to healthy tissues, reducing potential side effects.
• Reduced Treatment Time: SBRT/SABR typically involves a shorter treatment duration compared to conventional radiation therapy, with fewer sessions required (usually 1-5 sittings) (Conventional Radiation treatment is delivered daily, 5 days a week for 5-7 weeks duration on an average).
• Outpatient Treatment: Most patients can undergo SBRT/SABR on an outpatient basis, minimizing disruption to their daily lives.
• Enhanced Tumor Control: The higher Biologically Effective Dose (BED) of radiation delivered by SBRT/SABR contributes to more effective & higher tumor control and thereby improving clinical outcomes compared to Conventional Radiation Therapy.
• Personalized Treatment: Each SBRT/SABR treatment plan is tailored to the individual patient’s anatomy and tumor characteristics.
  
  

Patient Selection & Safety

Patient selection for SBRT/SABR involves careful evaluation of factors such as tumor size, location, and proximity to critical structures & mobility of the Tumor. The treatment’s safety and effectiveness rely on proper immobilization, Motion Management Systems, proper imaging for precise planning as well as Image Guidance system for precise treatment delivery and adherence to established protocols. Your medical team will determine if SBRT/SABR is appropriate for your specific case and provide guidance throughout the treatment process. The scope of SBRT is gradually increasing over multiple sub-sites & types of cancer globally.

Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Ablative Radiotherapy (SABR) exemplify the rapid advancements in radiation oncology, showcasing the potential to achieve remarkable tumor control while prioritizing patient well-being. As research and technology continue to progress, SBRT/SABR holds promise for expanding its applications and further refining cancer treatment strategies in the years to come.

For any queries on cancer radiation therapy, connect with our expert,Dr. Sandeep De, Consultant Radiation Oncology, at the best cancer hospital in Mumbai-Apollo Cancer Centres, Navi Mumbai.

Call 022 6280 6280 for an appointment.