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Hemodiafiltration

Hemodiafiltration (HDF) is a renal replacement therapy method designed to purify the blood by combining convective and diffusive driving forces, unlike standard hemodialysis, which relies solely on diffusion. In comparison to standard hemodialysis, HDF excels at extracting a greater amount of middle-molecular-weight solutes from the blood.

HDF typically offers:

Enhanced clinical outcomes
Sufficient convection volumes
Enhanced clearance of larger toxins.

At Apollo Hospital in Jubilee Hills, Hyderabad, we provide more than just diagnosing and treating patients. Our dedicated doctors ensure each individual receives comprehensive healthcare services, employing cutting-edge technology to enhance recovery and promote overall wellness.

Why Choose Hemodiafiltration?

Compared to conventional dialysis, which relies only on the diffusion principle, hemodiafiltration (HDF) offers improved survival rates for patients.
Studies have shown that patients tolerate HDF better than hemodialysis, experiencing fewer episodes of low blood pressure.
HDF effectively eliminates middle molecular toxins such as phosphorus, beta-two microglobulin, and inflammatory cytokines.
There is a reduced occurrence of complications like dialysis-related amyloidosis.
HDF aids in the better management of renal bone disease.
Furthermore, HDF leads to decreased levels of pro-inflammatory cytokines, resulting in reduced cardiovascular mortality, less itching, improved nutrition, and enhanced control of anaemia.

What Happens In Hemodiafiltration?

Step 1:

To initiate the dialysis process, a trained dialysis nurse or technician carefully inserts two needles into a suitable vein in the patient’s arm. These needles are precisely positioned to allow for efficient removal and return of blood during the procedure. The needles are connected to flexible tubes, which are in turn linked to the dialysis machine.

Step 2:

Once the needles are in place, the dialysis machine takes over, playing a crucial role in filtering the patient’s blood. The machine pumps the blood through a specialised filter called a dialyzer, which acts as an artificial kidney. Within the dialyzer, waste products, excess fluids, and toxins are removed from the blood, while essential nutrients and substances are retained.

Throughout the dialysis session, the machine carefully monitors the patient’s blood pressure to ensure stability and safety. Additionally, the machine regulates the:

Blood flow through the filter: The rate at which blood flows through the dialyzer is adjusted based on the patient’s individual needs and condition. This optimisation helps to maximise the effectiveness of the dialysis process.
Removal of fluid from the body: One of the primary goals of dialysis is to remove excess fluid that has accumulated in the body, often due to kidney dysfunction. The dialysis machine carefully controls the rate at which fluid is removed, preventing dehydration or fluid overload complications.

By continuously monitoring and regulating these parameters, the dialysis machine helps to ensure a safe and effective dialysis session, promoting the overall well-being of the patient.

Potential Risks Associated With Hemodiafiltration

The risks of hemodiafiltration (HDF) vary based on factors like the patient’s health, equipment quality, and medical team expertise. Common risks include:

Low blood pressure
Infections at needle insertion sites
Blood clotting
Fluid imbalances
Electrolyte imbalances
Vascular access issues
Cardiovascular problems
Allergic reactions to equipment materials.

Regular monitoring by a skilled team and adherence to a personalised treatment plan are crucial to minimise these risks. Following infection control measures and maintaining vascular access are also important for safe HDF therapy.

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FAQ's

Patients with end-stage renal disease (ESRD) who require regular dialysis are potential candidates for HDF. However, suitability depends on various factors, including the patient's overall health and vascular access.

HDF sessions usually last around 3-5 hours and are typically performed three times a week, similar to standard hemodialysis.

Patients can manage side effects by following dietary and fluid restrictions, taking prescribed medications, and communicating any symptoms to their healthcare team promptly.