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Genomics

Apollo Hospitals in Jubilee Hills is recognised as one of the best hospitals for the evaluation and management of genetic disorders in Hyderabad. Our expertise spans across specialties and addresses genetic conditions arising in consanguineous marriages, pregnancies, infancy, childhood, and early and late-onset adulthood.

We regularly encounter various conditions such as infertility, pregnancy scan abnormalities, unexplained death of a baby within the womb or after birth, and delay or inability to walk or talk. Other conditions include persistent seizures, birth defects, vision or hearing impairment, mentally challenged or autistic children, abnormal facial features, poor child growth or short stature, bending or fractures of bones, abnormal walking in children or adults, cancer in multiple members of the family, early loss of memory, abnormal movements, and more.

Our expert domain also includes ‘Pharmacogenomics’, which means identifying genetic factors that help us choose the right medications for cancer and transplant procedures and prevent adverse effects of medications. Our institute consists of a qualified and experienced medical or clinical geneticist and a certified genetic counsellor, supported by a team of occupational therapists, physiotherapists, psychologists, nutritionists, and speech-language therapists.

Together, we offer integrated rehabilitative and well-rounded supportive care to address the medical, psychological, familial, and reproductive needs of the patients and their families. Once a genetic disease has been identified, we also offer valuable advice on how to prevent the disorder in future generations.

At Apollo’s Genomics Institutes in Jubilee Hills, Hyderabad, our goal is to identify genetic conditions early, counsel families for effective and timely management, and provide comprehensive care for individuals, couples, and families via a skilled multidisciplinary team. For some conditions, we also strive to source orphan drugs and enrol patients in suitable clinical trials, wherever indicated. Our genetic diagnostic samples are streamed through highly accredited labs to ensure the accuracy and confidentiality of the patient’s genetic reports. We also partner with research labs in our quest to diagnose difficult or undiagnosed rare disorders.

Our Specialised Clinics

At Apollo Hospitals in Jubilee Hills, Hyderabad, we understand the complexities of genetic disorders and the importance of customised care for each individual. To cater to the diverse needs of patients dealing with genetic conditions, our Genomic Institute offers specialised clinics focusing on specific areas:

Preventive Genomics
Cardio Genomics
Gastro Genomics
Nephro Genomics
Neuro Genomics
Pulmonary Genomics
Paediatric Genomics
Onco Genomics

Conditions We Treat

Genetic conditions can affect any age group, gender, and can have a significant impact on the entire family. Our geneticists are experienced in diagnosing and managing the following conditions.

Abnormal new-born screening report
Abnormal scan report in pregnancy
Congenital birth defects
Recurrent pregnancy losses
Primary infertility in a couple
Unexplained deaths in the womb, after birth, or in adulthood
Developmental delay in children
Poor growth
Recurrent infections in children
Intellectual disability
Blood disorders like thalassemia, sickle cell anaemia, haemophilia etc.
Inability to walk or an abnormal way of walking
Kidney or cardiac disorders diagnosed in the young
Abnormal-looking face or body
Bending or fracturing of bones
Abnormal genitalia at birth
Short stature
Cancers in multiple family members
Early dementia
Multiple deaths in the family due to similar symptoms

Clinical Genetic Evaluation

We gather detailed information about your family’s health history to understand any potential genetic conditions, how severe they might be, and how many family members are affected. Based on this information, we recommend the right genetic tests for you and provide counselling before the tests. After receiving your results, we offer post-test counselling to help you manage or prevent any identified genetic disorders effectively.

Diagnostics

The Genomics Institute at Apollo Hospitals, Jubilee Hills, Hyderabad, is equipped with state-of-the-art diagnostic technologies that adhere to international standards. Our comprehensive diagnostic services include:

Karyotype
Fluorescent In Situ Hybridization test (FISH)
MLPA
Fragment analysis
TP-PCR
Sanger sequencing
Multi-gene panel testing
Next generation sequencing (NGS)
Non-invasive prenatal testing (NIPT)
Chromosomal Microarray (CMA)
Optical Genome mapping

How to Spot a Genetic Disorder?

Look out for the following signs of a genetic disorder:

Several family members have the same health issue
The health problem is very serious and progressively worsens over time
The disorder affects multiple organs within the body
The condition remains undiagnosed even after multiple tests & consultations with different doctors
Treatments have not been effective in improving the symptoms
Many unexpected deaths have occurred in your family – young babies or adults

Genetic Counselling Services

Our genetic counselling services are provided by qualified counsellors who assist patients and families in understanding and managing the impact of a genetic diagnosis on the family. We offer compassionate support, dispense sensitive genetic information, and guide individuals and families through the complex terrain of genomics with care and support.

Whether you are navigating inherited conditions, exploring treatment options, or seeking to enrol in trials or patient support groups, our genetic counsellors are here to provide personalised care and empower you to make informed decisions about your genetic health.

Treatments

Our team of medical geneticists and genetic counsellors at Apollo Hospitals, Jubilee Hills, Hyderabad, offers treatments and therapeutic interventions wherever feasible for genetic conditions, ensuring optimal patient outcomes. They formulate specialised dietary therapies for patients with inborn errors of metabolism (IEM). They network with other specialists to arrange for timely transplant procedures, which may be curative for some genetic disorders.

Our team can be contacted for information on the availability of advanced therapies for genetic conditions, enrolment in appropriate clinical trials, or sourcing orphan drugs for specific conditions. The other available therapeutic options for some of the genetic conditions include enzyme replacement therapy (ERT), immunotherapy, targeted therapies for cancer, gene therapies, mRNA therapies, and more.

Academic and Research Activities

Genomics is a dynamic landscape with novel genes discovered every day. It is important to stay updated with this information to deliver the best care for our patients. We have rigorous academic sessions at both intra and interdepartmental levels, which helps the team stay abreast of the latest breakthroughs in genomics.

We are part of the Pan-Apollo Genomic Network, a group of experts including professors, geneticists, and counsellors. The team meets regularly to discuss difficult or unsolved cases, share clinical experiences, and formulate patient-friendly policies and decisions to optimise management. We also work together on creating easy-to-understand educational material and connecting you with support groups and research institutes for answers.

FAQ's

Genetic disorders happen when there are changes in your DNA, which leads to abnormal proteins and impairs the development, functioning, and maintenance of living organisms. These changes, also called mutations, can be passed down from parents or can start fresh in a single person. They affect how your body works and can lead to different health issues.

A medical or clinical geneticist is a medical doctor sub-specialising in evaluating and managing genetic disorders. Medical geneticists are thoroughly trained in complex concepts and intricacies of genetics, recognizing and managing genetic disorders, understanding the strengths and limitations of various genetic tests, and expert interpretation of the genetic results. They can guide you to appropriate tests, reduce the time to diagnosis, and offer valuable scientific expertise on how to manage the disease.

Genetic counselling is a process that helps individuals and families understand the genetic aspects of their health. Key counselling points about the disease and testing options will be first offered by the medical geneticist. Genetic counsellors continue the dialogue with families and provide them with appropriate ancillary information for addressing their emotional and psychological needs. They also summarise the key concepts for patients and their families, enabling them to make informed decisions on testing, care, and prevention.

Individuals and couples can reduce their risk of genetic disorders by taking precautions. Seek consultation with our medical geneticist, in the following scenarios:

Before starting a family, especially if there is consanguinity
If specific hereditary conditions are known in your family
Pregnancy scans have revealed abnormalities
Unexplained deaths in the family

Early identification of the genetic disorder helps in instituting timely interventions, which can improve outcomes and effective disease prevention in the next generation.

Most of the key information on testing is provided upfront by the doctor via ‘pre-test counselling’. Genetic testing is usually safe and does not involve any invasive procedures, but you may seek to clarify any doubts, concerns, or questions you may have, before doing the test. Our genetic counsellors at Apollo Hospitals, Jubilee Hills, Hyderabad, are here to help. They will talk with you about any possible risks or side effects and make sure you know exactly what to expect from the testing process.

To make the most of the appointment, at Apollo Hospitals in Jubilee Hills, Hyderabad, we recommend bringing the patient along with relevant medical records of the patient or family members. In the case of minors, parents or guardians who live with the child need to accompany them. The average consulting time for each patient will be 45 minutes to 1 hour. The doctor then gives the appropriate medical advice to the family. During the session, any questions or concerns you may have about patient health may be clarified. Our genetic counsellors will then work closely with you to address your ancillary needs and provide personalised guidance and support.

At Apollo Hospitals, Jubilee Hills, Hyderabad, we prioritise patient privacy and confidentiality throughout the genetic testing and counselling process. We adhere to strict privacy protocols and comply with applicable laws and regulations to safeguard patient information and maintain confidentiality at all times.

Genetic testing involves collecting a sample (such as blood, saliva, or tissue) from the patient and analysing it for specific genetic variations or mutations. The time taken to receive test results may vary depending on the type of test performed and the complexity of the analysis. Our team aims to provide timely and accurate results to patients undergoing genetic testing. How can I schedule an appointment with the Apollo Hospitals Genomics Institutes, Jubilee Hills, Hyderabad? To schedule an appointment with our Genomics Institutes or learn more about our services, please contact: [ Phone no ] or Visit: [ Website ]

Choose Apollo Hospitals, Jubilee Hills, Hyderabad for genetic disorders because we lead the way in genomics, offering state-of-the-art diagnostic technologies and a multidisciplinary team of experts including genetic consultants and counsellors. As part of the Pan-Apollo Genomic Network, we stay updated with the latest advancements in genomics to provide expert guidance tailored to your needs. Recognised as the only corporate, multi-specialty hospital with medical genetics services, we offer comprehensive and multi-dimensional care to patients and families struggling with rare disorders. Our goal is to ensure that genetic patients are no longer ignored and given the due attention, care, and support they deserve. We also strive to harness the latest advances in genomics in our clinical practice so that the most personalised treatment is possible.