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      Can amlodipine and remdesivir help in Corona virus infection ?

      Cardiology Image 1 Verified By April 23, 2020

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      Can amlodipine and remdesivir help in Corona virus infection ?

      Remdesivir was previously tested as an Ebola virus treatment. It has generated promising results in animal studies for Middle East Respiratory Syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS), which are also caused by coronaviruses, suggesting it may have some effect in patients with COVID-19. Phase 3 investigational studies are currently on.
      Retrospective clinical investigation of COVID-19 patients in a study has revealed that the amlodipine administration distinctly reduced the case fatality rate of patients with hypertension. Results from this study suggest that Calcium channel blocker administration for COVID-19 patients with hypertension might improve the disease outcome. [Quoting from a yet to be peer-reviewed pre-print study from Wuhan by Leike Zhang, Yuan Sun, Hao-Long Zeng, Yudong Peng, Xiaming Jiang, Wei-Juan Shang, Yan Wu, Shufen Li, Yu-Lan Zhang, Liu Yang, Hongbo Chen, Runming Jin, Wei Liu, Hao Li, Ke Peng, Gengfu Xiao : “Calcium channel blocker amlodipine besylate is associated with a reduced case fatality rate of COVID-19 patients with hypertension”.

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