Verified By Apollo Hospitals October 1, 2024
Empty Sella Syndrome (ESS) is a neurological disorder in which the pituitary gland either gets flattened or shrinks due to the enlargement of the sella turcica. It is a bony structure that surrounds and protects the pituitary gland and is present at the base of the brain. The disorder gets its name because, during imaging tests of the sella turcica, the shell may appear to be empty. Empty Sella Syndrome causes symptoms such as hormonal imbalances, frequent headaches, and vision problems.
The blog explains Empty Sella Syndrome, its symptoms, types, causes, and various treatment options.
In a human skull, a small, bony nook is at the base of the brain that surrounds, holds, and protects the pituitary gland – it controls and regulates the various hormones in a body. The tiny structure is the sella turcica, which gets its name from a Latin word, ‘Turkish seat.’
In a few people, the sella turcica is developed in a manner where the spinal fluid can easily enter the structure. The build of the spinal fluid flattens the pituitary gland making it look like the sella turcica is empty. Doctors often detect this disorder when looking for causes of other problems.
ESS is more likely to develop in women than men. People with high blood pressure and suffering from obesity are also at a higher risk of developing ESS.
When a doctor diagnoses a patient with Empty Sella Syndrome, they categorize the disorder into two categories. The two types of ESS are as follows:
Often Empty Sella Symptoms do not show any signs or symptoms. Depending on age, symptoms may differ from person to person, and doctors believe only 1% of patients show symptoms. If a patient notices symptoms, they may be as follows:
Some of the lesser-known symptoms include the following:
The function of the pituitary gland in the empty sella syndrome is generally not affected. While it’s often not well seen on imaging, it is perfectly functional otherwise. The pituitary is a small gland situated close to the base of your skull that stores numerious critical hormones and releases these harmones into the bloodstream as required by the body. These hormones regulate various different functions of the body. Although a rarely, some decreased or abnormal pituitary function can happen (hypopituitarism) in the setting of empty sella. A detailed finding in some people with empty sella, like children, has been the isolated growth hormone deficiency.
Consult a doctor if the symptoms worsen or have newer symptoms.
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The causes of primary and secondary Empty Sella Syndrome are different. The cause of primary ESS is unknown. However, healthcare providers believe it is due to a congenital disability.
The reason for secondary ESS is due to damage in the sella turcica as a result of other health conditions. The following are the causes of the damage:
Empty Sella Syndrome is challenging to diagnose. But it is most often found when searching for a cause for another medication. The healthcare provider takes details about medical history and conducts a physical examination. The doctor may also prescribe the following tests:
In rare cases, the patient may show symptoms of ESS. In such cases, the doctor may order several tests, including the following:
Based on the age, symptoms, medical history of previous treatments or surgeries, and duration of the condition, the doctor, treats ESS. However, most cases of ESS do not require any treatment. In rare instances in which the symptoms hamper the daily life of a patient, the doctor may use the following treatment options:
However, if a patient suffers from secondary ESS due to another medical condition, the doctor starts treating the underlying medical condition to eliminate or manage the symptoms of ESS.
The prognosis is good for patients with no symptoms and does not affect their overall health. If a patient has symptoms, it is easily treatable with medications and surgery. A person can lead a healthy, long life with a proper diagnosis.
ESS is not life-threatening. It is treatable with medications and surgery.
Women are four times more likely to develop Empty Sella Syndrome than men. Primary Empty Sella Syndrom occurs between 30 to 40 years.
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