Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC)
Introduction
Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) is a novel treatment modality for patients with refractory peritoneal cancers due to metastasis of gastrointestinal and gynecological malignancies.
Procedures
PIPAC is a minimally invasive procedure done under general anesthesia through Laparoscopic approach. Using the video camera, the extent of the peritoneal disease is documented and the specialized device…
Indications
Cancers that spread to the peritoneal cavity benefit from PIPAC, and these include:
- Ovarian
- Gastric
- Colorectal
- Appendecial
Advantages
- PIPAC is typically placed as an adjunct for systemic chemotherapy in between the cycles of chemotherapy. Hence systemic chemotherapy treats primary tumor and distant disease whereas PIPAC treats the peritoneal disease.
