Sickle cell disease is genetic – to have it, children must get 2 faulty genes – one from each parent. Namely, the condition of an autosomal recessive pattern, which means both copies of the gene in each cell have mutations.
More common in those with ancestors from people of Africa, India, and Mediterranean
Develop symptoms when the body is exposed to some stress condition like fever, dehydration(loss of water), being at high altitudes, pregnancy, acute blood loss(e.g., GI bleeding)
