PET CT accesses spread to regional nodes or distant
metastases to other body parts. It provides functional and
morphological details by utilising radiation derived from Isotope
labelled Glucose molecules to detect cellular glucose uptake, in
cancer.
Lymph node biopsy – The lymph node may be removed during an
image-guided CT
scan thoracoscopy, mediastinoscopy or laparoscopy.
They may remove the lymph node and send it for further evaluation.
Bone marrow aspiration and biopsy – In this procedure, a
sample of bone marrow and a small piece of bone is collected by
inserting a hollow needle into the hipbone or breastbone.
Blood Test – Complete blood count (CBC), Liver and
Renal function tests.
Pathology
– The tissue and marrow samples
collected are sent for further evaluation, such as
Histopathological examination (HPE), cytology and
Immunohistochemistry (IHC), to determine the type of disease and
its grading.
Immunohistochemistry – It uses antibodies to
identify cancer cells based on the types of antigens or markers
on the surface of the cells. This test helps diagnose specific
types of lymphoma
Flow cytometry – A laboratory test that measures
the number of cells in a sample, the percentage of live cells in
a sample, and specific characteristics of the cells, such as
size, shape, and the presence of tumour (or other) markers on
the cell surface.
Chromosomal Testing – Cytogenetic analysis, FISH –
Fluorescence in situ hybridization