- Sex- Men are at a higher risk
- Age- More common in people over the age of 60
- Smoking increases the risk
- Alcohol Consumption
- Diet – Diets high in red meat and salted or smoked foods increases the risk of small intestine cancer
- Inherited syndromes – People with certain inherited conditions like
- Familial adenomatous polyposis (FAP)
- Peutz-Jeghers syndrome (PJS)
- Hereditary nonpolyposis colon cancer (HNPCC)
- Autoimmune Conditions – Autoimmune inflammatory bowel diseases like Crohn’s Disease and Celiac sprue increase the risk of small bowel cancers
- Immunosuppression – People who are immunosuppressed (post-organ transplant or in conditions like HIV) are at a higher risk of developing Jejunal cancers.
