While the exact cause for colorectal cancer is unknown, there are certain factors that may increase the risk of developing colorectal cancer. Some of these factors are: Age – Colorectal cancer usually affects people over the age of 50. History – Patients with Inherited syndromes – Familial Adenomatous Polyposis (FAP) and Lynch syndrome also known as Hereditary Non Polyposis Colorectal Cancer (HNPCC). Inflammatory intestinal conditions – Ulcerative colitis and Crohn’s disease Hormone Replacement Therapy (HRT) – In post-menopausal women Family history of colorectal cancer. Exposure to radiation – Radiation to treat previous cancers in the abdominal region. Diabetes – People with diabetes or insulin resistance Lifestyle factors such as Sedentary lifestyle